Ecotoxicology of phenylphosphonothioates.

نویسندگان

  • B M Francis
  • L G Hansen
  • T R Fukuto
  • P Y Lu
  • R L Metcalf
چکیده

The phenylphosphonothioate insecticides EPN and leptophos, and several analogs, were evaluated with respect to their delayed neurotoxic effects in hens and their environmental behavior in a terrestrial-aquatic model ecosystem. Acute toxicity to insects was highly correlated with sigma sigma of the substituted phenyl group (regression coefficient r = -0.91) while acute toxicity to mammals was slightly less well correlated (regression coefficient r = -0.71), and neurotoxicity was poorly correlated with sigma sigma (regression coefficient r = -0.35). Both EPN and leptophos were markedly more persistent and bioaccumulative in the model ecosystem than parathion. Desbromoleptophos, a contaminant and metabolite of leptophos, was seen to be a highly stable and persistent terminal residue of leptophos.

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عنوان ژورنال:
  • Environmental Health Perspectives

دوره 36  شماره 

صفحات  -

تاریخ انتشار 1980